Awesome Python

An Open Source Machine Learning Framework for Everyone

Tensors and Dynamic neural networks in Python with strong GPU acceleration

A high-throughput and memory-efficient inference and serving engine for LLMs

The Python programming language

Ultralytics YOLO26, YOLO11, YOLOv8 — object detection, instance segmentation, semantic segmentation, image classification, pose estimation, object tracking

C++ based gRPC (C++, Python, Ruby, Objective-C, PHP, C#)

DuckDB is an analytical in-process SQL database management system

Composable transformations of Python+NumPy programs: differentiate, vectorize, JIT to GPU/TPU, and more

A browser automation framework and ecosystem.

The fundamental package for scientific computing with Python.

SGLang is a high-performance serving framework for large language models and multimodal models.

Scalable, Portable and Distributed Gradient Boosting (GBDT, GBRT or GBM) Library, for Python, R, Java, Scala, C++ and more. Runs on single machine, Hadoop, Spark, Dask, Flink and DataFlow

MicroPython - a lean and efficient Python implementation for microcontrollers and constrained systems

Open-source speech recognition toolkit for training, inference, streaming ASR, VAD, punctuation, speaker diarization pipelines, and OpenAI-compatible/MCP serving.

A fast, distributed, high performance gradient boosting (GBT, GBDT, GBRT, GBM or MART) framework based on decision tree algorithms, used for ranking, classification and many other machine learning tasks.

Build realtime web, mobile and desktop apps in Python only. No frontend experience required.

Dear PyGui: A fast and powerful Graphical User Interface Toolkit for Python with minimal dependencies

A lightweight, lightning-fast, in-process vector database

Approximate Nearest Neighbors in C++/Python optimized for memory usage and loading/saving to disk

Scalene: a high-performance, high-precision CPU, GPU, and memory profiler for Python with AI-powered optimization proposals

A fast, scalable, high performance Gradient Boosting on Decision Trees library, used for ranking, classification, regression and other machine learning tasks for Python, R, Java, C++. Supports computation on CPU and GPU.

Qiskit is an open-source SDK for working with quantum computers at the level of extended quantum circuits, operators, and primitives.

the portable Python dataframe library

Coroutine-based concurrency library for Python

Powerful, mature open-source cross-platform game engine for Python and C++, developed by Disney and CMU

A static type analyzer for Python code

Fast Python Collaborative Filtering for Implicit Feedback Datasets

The official sources for the RDKit library

Codebase intelligence for AI and humans: code health scores, auto-generated docs, git analytics, dead code detection, and architectural decisions via MCP.

A Python library for reading and writing PDF, powered by QPDF

Open Babel is a chemical toolbox designed to speak the many languages of chemical data.

Python bindings for MPI

The fastest PDF library for Python and Rust. Text extraction, image extraction, markdown conversion, PDF creation & editing. 0.8ms mean, 5× faster than industry leaders, 100% pass rate on 3,830 PDFs. MIT/Apache-2.0.

Desbordante is a high-performance data profiler that is capable of discovering many different patterns in data using various algorithms. It also allows to run data cleaning scenarios using these algorithms. Desbordante has a console version and an easy-to-use web application.

Microsoft Python Driver for SQL Server

Multibody dynamics tool kit.

Git super project for PySide